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Index > Protein center > Nfam1(Gene name) > Mouse
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  • Nfam1 (Gene name),
  • NFAT activation molecule 1 (Protein name ),  NFAM1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Nfam1(Cnaip);
    Protein name:
    NFAT activation molecule 1;
    Alternative:
    NFAT-activating protein with ITAM motif 1;Calcineurin/NFAT-activating ITAM-containing protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with ZAP70 and SYK. No direct interaction with the B-cell antigen receptor (BCR).
    Function:
    May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters (By similarity). May be involved in the regulation of B-cell, but not T-cell, development.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Partially recruited to lipid rafts upon BCR stimulation.
    Protein Attributes:
    Sequence length:
    264
    Sequence:
    50:
    MESWLLRRGA | RVRCLHPPSW | LPAWCFLCLL | PVPQTLQLTG | LVSLTHTSLP | 
    100:
    IMVSLANTDV | FFSCRIEDFT | RLQRDLPVKL | FHTDIHGRRR | WEKQINCQHR | 
    150:
    PGMENHTRDC | MVKLSQANTS | ATGIYYFIVE | GEETYQSDGV | VILVRDTVYQ | 
    200:
    PPAFKVQEAL | MLGFTSLMSV | LGVLGTALLL | WKKKQISVLG | KHTAKTCSGL | 
    250:
    KSTVGTTKPP | AESVYTSLQR | RETEVYACMK | EETGSPVFSQ | SPATKEKLNR | 
    264:
    FEDDNEFNLV | YENL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse NFAT activation molecule 1
    Cat.:
    E3904m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse NFAT activation molecule 1
    Cat.:
    E3904h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Mouse NFAT activation molecule 1
    Cat.:
    U3904m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NFAT activation molecule 1
    Cat.:
    U3904h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse NFAT activation molecule 1
    Cat.:
    P3904Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NFAT activation molecule 1
    Cat.:
    P3904Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse NFAT activation molecule 1
    Monoclonal Antibody for Mouse NFAT activation molecule 1
    Protein for Mouse NFAT activation molecule 1
    Protein for Mouse NFAT activation molecule 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling."
      Ohtsuka M. , Arase H. , Takeuchi A. , Yamasaki S. , Shiina R. , Suenaga T. , Sakurai D. , Yokosuka T. , Arase N. , Iwashima M. , Kitamura T. , Moriya H. , Saito T.
      Proc. Natl. Acad. Sci. U.S.A.101:8126-8131(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;GLYCOSYLATION;DEVELOPMENTAL STAGE;INTERACTION WITH SYK AND ZAP70
      strain: C57BL/6.
      tissue: Spleen.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Bone marrow.
      tissue: Cerebellum.
      tissue: Spinal cord.
      tissue: Testis.
    3. 3.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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